Browsing AECC University College Research Collection by Author "Breen, Alan"
Now showing items 1-20 of 26
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Aberrant intervertebral motion in patients with treatment-resistant nonspecific low back pain: a retrospective cohort study and control comparison
Breen, Alex; Mellor, Fiona; Breen, Alan (European Spine Journal, 2018)Purpose: Intervertebral kinematic assessments have been used to investigate mechanical causes when back pain is resistant to treatment, and recent studies have identified intervertebral motion markers that discriminate ... -
Accuracy and repeatability of quantitative fluoroscopy for the measurement of sagittal plane translation and finite centre of rotation in the lumbar spine
Breen, Alex; Breen, Alan (Medical Engineering and Physics, 2016)Quantitative fluoroscopy (QF) was developed to measure intervertebral mechanics in vivo and has been found to have high repeatability and accuracy for the measurement of intervertebral rotations. However, sagittal plane ... -
Anti-directional cervical intervertebral motion: could it have gone any other way?
Breen, Alan (Journal of Spine Surgery, 2018) -
Association of spinal manipulative therapy with changes in cervical motion segment interactions in patients with neck pain: an observational study with matched asymptomatic controls
du Rose, Alister; Branney, Jonathan; Breen, Alan (Journal of Manipulative and Physiological Therapeutics, 2021)Objective: The objectives of this study were to determine (1) if maximal intervertebral range of motion (IV-RoMmax) and laxity interactions exist in the cervical spine during flexion, (2) if there are differences in IV-RoMmax ... -
Can biomechanics research lead to more effective treatment of low back pain? A point-counterpoint debate
Cholewicki, Jacek; Breen, Alan; Popovich Jr, John M; Reeves, N Peter; Sahrmann, Shirley A; van Dillen, Linda R; Vleeming, Andry; Hodges, Paul W (Journal of Orthopaedic and Sports Physical Therapy, 2019)Although biomechanics plays a role in the development and perhaps the persistent or recurrent nature of low back pain (LBP), whether biomechanics alone can provide the basis for intervention is debated. Biomechanics, which ... -
Comparison of intra subject repeatability of quantitative fluoroscopy and static radiography in the measurement of lumbar intervertebral flexion translation
Breen, Alex; Claerbout, Emilie; Hemming, Rebecca; Ayer, Ravi; Breen, Alan (Scientific Reports, 2019)Low back pain patients are sometimes offered fusion surgery if intervertebral translation, measured from static, end of range radiographs exceeds 3 mm. However, it is essential to know the measurement error of such methods, ... -
Does cervical lordosis change after spinal manipulation for non-specific neck pain? A prospective cohort study
Shilton, Michael; Branney, Jonathan; Penning de Vries, Bas; Breen, Alan (Chiropractic and Manual Therapies, 2015)Background: The association between cervical lordosis (sagittal alignment) and neck pain is controversial. Further, it is unclear whether spinal manipulative therapy can change cervical lordosis. This study aimed to determine ... -
Does inter-vertebral range of motion increase after spinal manipulation? A prospective cohort study
Branney, Jonathan; Breen, Alan (Chiropractic and Manual Therapies, 2014)Background: Spinal manipulation for nonspecific neck pain is thought to work in part by improving inter-vertebral range of motion (IV-RoM), but it is difficult to measure this or determine whether it is related to clinical ... -
Dynamic interactions between lumbar intervertebral motion segments during forward bending and return
Breen, Alex; Breen, Alan (Journal of Biomechanics, 2020)Continuous dynamic multi-segmental studies of lumbar motion have added depth to our understanding of the biomechanics of back pain, but few have attempted to continuously measure the proportions of motion accepted by ... -
Estimation of in vivo inter-vertebral loading during motion using fluoroscopic and magnetic resonance image informed finite element models
Zanjani-Pour, Sahand; Meaking, Judith R; Breen, Alex; Breen, Alan (Journal of Biomechanics, 2018)Finite element (FE) models driven by medical image data can be used to estimate subject-specific spinal biomechanics. This study aimed to combine magnetic resonance (MR) imaging and quantitative fluoroscopy (QF) in ... -
An in-vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine
Breen, Alan; Mellor, Fiona; Morris, Andrew; Breen, Alex (European Spine Journal, 2020)Purpose: Early disc degeneration (DD) has been thought to be associated with loss of spine stability. However, before this can be understood in relation to back pain, it is necessary to know the relationship between DD and ... -
Intrasubject repeatability of in vivo intervertebral motion parameters using quantitative fluoroscopy
Breen, Alex; Hemming, Rebecca; Mellor, Fiona; Breen, Alan (European Spine Journal, 2019)Purpose: In vivo quantification of intervertebral motion through imaging has progressed to a point where biomarkers for low back pain are emerging. This makes possible deeper study of the condition’s biometrics. However, ... -
Investigator analytic repeatability of two new intervertebral motion biomarkers for chronic, nonspecific low back pain in a cohort of healthy controls
To, Daphne; Breen, Alex; Breen, Alan; Mior, Silvano; Howarth, Samuel (Chiropractic and Manual Therapies, 2020)Background: Understanding the mechanisms underlying chronic, nonspecific low back pain (CNSLBP) is essential to advance personalized care and identify the most appropriate intervention. Recently, two intervertebral motion ... -
Low back pain: Identifying sub-groups, clinical prediction rules and measuring results
Breen, Alan (Complementary Therapies in Clinical Practice, 2018)Low back pain is a complex, multifactorial health problem with huge socioeconomic impact. The purpose of this brief review was to reconsider the use of the biopsychosocial model as a basis for subgrouping cases to support ... -
Manual therapy
Breen, Alan; Vogel, Steven; McCarthy, Christopher (International Society for the Study of the Lumbar Spine, 2018)Manual therapy (MT) is a very common practice among primates and its range of uses and the variety of techniques is probably infinite. It has been professionalised for the treatment of a variety of conditions for at least ... -
Measurement of intervertebral motion using quantitative fluoroscopy: report of an international forum and proposal for use in the assessment of degenerative disc disease in the lumbar spine
Breen, Alan; Teyhen, Deydre S; Mellor, Fiona; Breen, Alex; Wong, Kris W N; Deitz, Adam (Advances in Orthopedics, 2012)Quantitative fluoroscopy (QF) is an emerging technology for measuring intervertebral motion patterns to investigate problem back pain and degenerative disc disease. This International Forum was a networking event of three ... -
Moving back: The radiation dose received from lumbar spine quantitative fluoroscopy compared to lumbar spine radiographs with suggestions for dose reduction
Mellor, Fiona; Thomas, P; Breen, Alan (Radiography, 2014)Purpose: Quantitative fluoroscopy is an emerging technology for assessing continuous inter-vertebral motion in the lumbar spine, but information on radiation dose is not yet available. The purposes of this study were to ... -
Novel assessment of the variation in cervical inter-vertebral motor control in a healthy pain-free population
Lindstrøm, René; Breen, Alex; Qu, Ning; du Rose, Alister; Andersen, Victoria Blogg; Breen, Alan (Scientific Reports, 2021)Spinal control at intervertebral levels is dependent on interactions between the active, passive and neural control elements. However, this has never been quantifiable, and has therefore been outside the reach of clinical ... -
An objective spinal motion imaging assessment (OSMIA): reliability, accuracy and exposure data
Breen, Alan; Muggleton, Jennifer M; Mellor, Fiona (BMC Musculoskeletal Disorders, 2006)Background: Minimally-invasive measurement of continuous inter-vertebral motion in clinical settings is difficult to achieve. This paper describes the reliability, validity and radiation exposure levels in a new Objective ... -
Passive intervetebral motion characteristics in chronic mid to low back pain: A multivariate analysis
Brownhill, Kevin; Mellor, Fiona; Breen, Alex; Breen, Alan (Medical Engineering and Physics, 2020)Purpose: Studies comparing back pain patients and controls on continuous intervertebral kinematics have shown differences using univariate parameters. Hitherto, multivariate approaches have not been applied to this high ...