Browsing AECC University College Research by Author "Breen, Alex"
Now showing items 1-20 of 22
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Measurement of intervertebral motion using quantitative fluoroscopy: report of an international forum and proposal for use in the assessment of degenerative disc disease in the lumbar spine
Breen, Alan; Teyhen, Deydre S; Mellor, Fiona; Breen, Alex; Wong, Kris W N; Deitz, Adam (Advances in Orthopedics, 2012)Quantitative fluoroscopy (QF) is an emerging technology for measuring intervertebral motion patterns to investigate problem back pain and degenerative disc disease. This International Forum was a networking event of three ... -
Attainment rate as a surrogate indicator of the intervertebral neutral zone length in lateral bending: an in vitro proof of concept study
Breen, Alex; Dupac, Mihai; Osborne, Neil (Chiropractic and Manual Therapies, 2015)Background: Lumbar segmental instability is often considered to be a cause of chronic low back pain. However, defining its measurement has been largely limited to laboratory studies. These have characterised segmental ... -
Accuracy and repeatability of quantitative fluoroscopy for the measurement of sagittal plane translation and finite centre of rotation in the lumbar spine
Breen, Alex; Breen, Alan (Medical Engineering and Physics, 2016)Quantitative fluoroscopy (QF) was developed to measure intervertebral mechanics in vivo and has been found to have high repeatability and accuracy for the measurement of intervertebral rotations. However, sagittal plane ... -
Correlations between individuals’ characteristics and spinal stiffness in individuals with and without back pain: A combined analysis of multiple data sets
Pagé, Isabelle; Swain, Michael; Wong, Arnold; Breen, Alex; De Carvalho, Diana; Descarreaux, Martin; Funabashi, Martha; Kawchuk, Gregory (Journal of Manipulative and Physiological Therapeutics, 2018)Objective: The purpose of this study was to describe the correlations between individual characteristics and spinal stiffness as measured with different spinal stiffness measurement devices in individuals with and without ... -
Estimation of in vivo inter-vertebral loading during motion using fluoroscopic and magnetic resonance image informed finite element models
Zanjani-Pour, Sahand; Meaking, Judith R; Breen, Alex; Breen, Alan (Journal of Biomechanics, 2018)Finite element (FE) models driven by medical image data can be used to estimate subject-specific spinal biomechanics. This study aimed to combine magnetic resonance (MR) imaging and quantitative fluoroscopy (QF) in ... -
Relationships between muscle electrical activity and the control of inter-vertebral motion during a forward bending task
du Rose, Alister; Breen, Alex; Breen, Alan (Journal of Electro - myography and Kinesiology, 2018)Muscle strengthening exercises are commonly used in primary care for the treatment of chronic, non-specific low back pain (CNSLBP) as it has been theorised that increased muscle activity contributes to the stabilisation ... -
Aberrant intervertebral motion in patients with treatment-resistant nonspecific low back pain: a retrospective cohort study and control comparison
Breen, Alex; Mellor, Fiona; Breen, Alan (European Spine Journal, 2018)Purpose: Intervertebral kinematic assessments have been used to investigate mechanical causes when back pain is resistant to treatment, and recent studies have identified intervertebral motion markers that discriminate ... -
Uneven intervertebral motion sharing is related to disc degeneration and is greater in patients with chronic, non-specific low back pain: an in vivo, cross-sectional cohort comparison of intervertebral dynamics using quantitative fluoroscopy
Breen, Alan; Breen, Alex (European Spine Journal, 2018)Purpose: Evidence of intervertebral mechanical markers in chronic, non-specific low back pain (CNSLBP) is lacking. This research used dynamic fluoroscopic studies to compare intervertebral angular motion sharing inequality ... -
Leadership and capacity building in international chiropractic research: introducing the chiropractic academy for research leadership (CARL)
Adams, Jon; Kawchuk, Greg; Breen, Alex; De Carvalho, Diana; Eklund, Andreas; Fernandez, Matthew; Funabashi, Martha; Johansson, Melker S; de Luca, Katie; Moore, Craig; Pagé, Isabelle; Pohlman, Katherine A; Swain, Michael S; Wong, Arnold Y L; Hartvigsen, Jan; Holmes, Michelle (Chiropractic and Manual Therapies, 2018)In an evidence-based health care environment, healthcare professions require a sustainable research culture to remain relevant. At present however, there is not a mature research culture across the chiropractic profession ... -
Clinicians' ability to detect a palpable difference in spinal stiffness compared with a mechanical device
Kawchuk, Gregory N; Miazga, Stephen; Pagé, Isabelle; Swain, Michael; De Carvalho, Diana; Funabashi, Martha; Breen, Alex; Wong, Arnold (Journal of Manipulative and Physiological Therapeutics, 2019)Objective: The purpose of this study was to quantify the threshold at which clinicians can detect a difference in spinal stiffness of the thoracic and lumbar spine via palpation and then determine if this detection threshold ... -
Intrasubject repeatability of in vivo intervertebral motion parameters using quantitative fluoroscopy
Breen, Alex; Hemming, Rebecca; Mellor, Fiona; Breen, Alan (European Spine Journal, 2019)Purpose: In vivo quantification of intervertebral motion through imaging has progressed to a point where biomarkers for low back pain are emerging. This makes possible deeper study of the condition’s biometrics. However, ... -
Comparison of intra subject repeatability of quantitative fluoroscopy and static radiography in the measurement of lumbar intervertebral flexion translation
Breen, Alex; Claerbout, Emilie; Hemming, Rebecca; Ayer, Ravi; Breen, Alan (Scientific Reports, 2019)Low back pain patients are sometimes offered fusion surgery if intervertebral translation, measured from static, end of range radiographs exceeds 3 mm. However, it is essential to know the measurement error of such methods, ... -
Center of rotation locations during lumbar spine movements: a scoping review protocol
Funabashi, Martha; Breen, Alex; De Carvalho, Diana; Henry, Alison; Murnaghan, Kent; Pagé, Isabelle; Wong, Arnold; Kawchuk, Greg (JBI Database of Systematic Reviews and Implementation Reports, 2020)Objective: The objective of this review is to identify and map current literature describing the center of rotation locations and migration paths during lumbar spine movements. Introduction: The importance of lumbar ... -
Dynamic interactions between lumbar intervertebral motion segments during forward bending and return
Breen, Alex; Breen, Alan (Journal of Biomechanics, 2020)Continuous dynamic multi-segmental studies of lumbar motion have added depth to our understanding of the biomechanics of back pain, but few have attempted to continuously measure the proportions of motion accepted by ... -
An in-vivo study exploring correlations between early-to-moderate disc degeneration and flexion mobility in the lumbar spine
Breen, Alan; Mellor, Fiona; Morris, Andrew; Breen, Alex (European Spine Journal, 2020)Purpose: Early disc degeneration (DD) has been thought to be associated with loss of spine stability. However, before this can be understood in relation to back pain, it is necessary to know the relationship between DD and ... -
Investigator analytic repeatability of two new intervertebral motion biomarkers for chronic, nonspecific low back pain in a cohort of healthy controls
To, Daphne; Breen, Alex; Breen, Alan; Mior, Silvano; Howarth, Samuel (Chiropractic and Manual Therapies, 2020)Background: Understanding the mechanisms underlying chronic, nonspecific low back pain (CNSLBP) is essential to advance personalized care and identify the most appropriate intervention. Recently, two intervertebral motion ... -
Association of exposures to seated postures with immediate increases in back pain: A systematic review of studies with objectively measured sitting time
De Carvalho, Diana E; de Luca, Katie; Funabashi, Martha; Breen, Alex; Wong, Arnold Y L; Johansson, Melker S; Ferreira, Manuela L; Swab, Michelle; Kawchuk, Gregory Neil; Adams, Jon; Hartvigsen, Jan (Journal of Manipulative and Physiological Therapeutics, 2020)Objective: The purpose of this study was to conduct a systematic review of studies to determine whether sitting time measured objectively (by laboratory controlled time trial, direct observation, or wearable sensor) is ... -
Passive intervetebral motion characteristics in chronic mid to low back pain: A multivariate analysis
Brownhill, Kevin; Mellor, Fiona; Breen, Alex; Breen, Alan (Medical Engineering and Physics, 2020)Purpose: Studies comparing back pain patients and controls on continuous intervertebral kinematics have shown differences using univariate parameters. Hitherto, multivariate approaches have not been applied to this high ... -
Novel assessment of the variation in cervical inter-vertebral motor control in a healthy pain-free population
Lindstrøm, René; Breen, Alex; Qu, Ning; du Rose, Alister; Andersen, Victoria Blogg; Breen, Alan (Scientific Reports, 2021)Spinal control at intervertebral levels is dependent on interactions between the active, passive and neural control elements. However, this has never been quantifiable, and has therefore been outside the reach of clinical ... -
Stakeholder involvement in the development of trial material for a clinical trial
Rix, Jacqui; Branney, Jonathan; Breen, Alex; Sewell, Philip; Docherty, Sharon (Health Expectations, 2021)Background: Stakeholder involvement includes not just patients and public, but also those delivering treatment e.g. clinicians and students. Each stakeholder brings unique experiences to the process. The aim of this ...